Question 3: Describe the Dendra2 chromophore discovered in the 2VZX…

Question 3: Describe the Dendra2 chromophore discovered in the 2VZX structure. Make sure to include 1) the
tripeptide amino acid sequence that undergoes posttranslational self-modification chemistry (i.e. maturation), 2)
the full name of the chromophore, 3) a chemical structure of the mature chromophore (an embedded image of
the chromophore will work…you don’t have to draw this structure by hand), and 4) a hypothesis to explain why
chromophore maturation would not occur in a short peptide (e.g. a peptide containing 6 residues on either side
of the tripeptide sequence) that does not contain the rest of the Dendra2 protein sequence. (12 pts)

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